Viewing at use of glucagon-like peptide-1 in treatment of type 2 diabetes based on the secretion characters of incretins
- VernacularTitle:从肠促胰素分泌机制看胰升糖素样肽1在2型糖尿病治疗中的应用
- Author:
Xiaoying LI
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Incretin;
Glucagon-like peptide-1
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(4):后插1-后插4
- CountryChina
- Language:Chinese
-
Abstract:
Recently, in the field of pathogenesis and treatment of type 2 diabetes, incretin is a major breakthrough. Based on the knowledge about physiological mechanism, pathological characters, and clinical application, this review article summarized the mechanism of nutrients ( glucose, fat, and protein) mediated incretin secretion, the impairment of incretin secretion and action in type 2 diabetes and glucagon-like peptide-1 's use in type 2 diabetic patients.
