The Development of Research on the Carboplatin Polymer System
- VernacularTitle:卡铂缓释剂的研究进展
- Author:
Wei XU
;
Ji ZHANG
- Publication Type:Journal Article
- From:
Journal of Kunming Medical University
2001;22(1):100-102，107
- CountryChina
- Language:Chinese
-
Abstract:
Glioma is the most common tumor in craniocerebra l neoplasms． It is hard to deal with for every neurosurgery not the difficulty o f operation,but the poor outcome． Many efforts was made in this area include ne w drugs in chemotherapy; intratumoral radiation, stereostatic radioneurosurgery in neuroradiation, and the new strategy of operation direct to tumor． Local intratumoral implants carried by biodegradable polymer provide a new promising approach for more selective and less neurotoxic in chemotherapy． The polymer microsphere carried with carboplatin is much powerful to glioma in vitro and in vivo． The disadvantages of carboplatin during delivery systemically disappeared．
