Toxic Effect of Organic Extracts From Chlorinated Drinking Water on Sertoli Cells of Testis in Rats
- VernacularTitle:氯化饮用水有机提取物对睾丸支持细胞的毒性效应研究
- Author:
Huaijun TIAN
;
Desheng WU
;
Rui TAO
- Publication Type:Journal Article
- From:
Journal of Environment and Health
2001;18(3):146-147,189
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the potential hazards of organic pollutants in chlorinated drinking water on human reproduction.Methods The reproductive toxicity of the organic pollutants extracted by solid phase extraction technique from chlorinated drinking water in a city,was determined by the co-culture of sertoli cells and spermatogenic cells.Results No significant variation of the rate of detached spermatogenic cells was noticed compared with the control rats.The organic extracts stimulated the secretion of lactate from sertoli cells of testis in rats.Conclusion The organic extracts of chlorinated drinking water revealed potential reproductive toxicity.