Determination of the Content of Glycols in Chloramphenicol Eye Drops With HPLC Method
- VernacularTitle:高效液相色谱法测定氯霉素滴眼液中的二醇物
- Author:
Jianwei TENG
;
Qichang DAI
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(5):301-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish a method for detecting glycols in chloramphenicol eye drops METHODS: HPLC method was used with C18 column as stationary phase and methanol- 0 4% phosphoric acid( 55∶ 45) as mobile phase The detection wavelength was 245nm RESULTS: The average recovery was 98 5% ( RSD=0 86% ) CONCLUSION: The method is simple, reliable and suitable for detecting glycols in chloramphenicol eye drops