Effect of Botulinum Toxin Type a Chemodenervation in Esotropia.
- Author:
Sang Yoon OH
1
;
Mi Ah SHON
;
Joo Yeon LEE
;
Min Cheol SHIN
Author Information
1. Department of Ophthalmology, College of Medicine, Hallym University, Chunchon sacred heart hospital, Korea. smcheol0@hanmail.net
- Publication Type:Original Article
- Keywords:
Botulinum toxin chemodenervation;
Partial accommodative ET
- MeSH:
Botulinum Toxins*;
Botulinum Toxins, Type A*;
Esotropia*;
Humans;
Nerve Block
- From:Journal of the Korean Ophthalmological Society
2004;45(1):112-116
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the efficacy of botulinum toxin type A chemodenervation in various types of esotropia(ET). METHODS: Enrolled eleven esotropic patients treated with botulinum toxin type A and examined the amount of esotropic correction and success rate of less than 10 PD (prism diopter) of postinjection deviation at 5 months after injection. RESULTS: Among the eleven esotropic patients, there were 7 cases of infantile ET, 2 cases of partially accommodative ET and 2 cases of basic ET. The mean preinjection deviation was 30.5 +/- 7.3 PD. The amount of correction was 17.7 +/- 4.3 PD and correction rate of deviation was 57.5%. In 6 of 11 cases, the postinjection deviation was within 10 PD and therefore success rate was 54.5%. In 5 patients (45.5%), their ET was undercorrected. In patients with under 20 PD of preinjection deviation, success rate was 75% (3/4) and those with over 20PD, the rate was 42.9% (3/7). In partially accommodative ET, 2 (100%) of 2 cases were aligned within 10PD. CONCLUSIONS: In comitant ET, botulinum toxin chemodenervation shows high undercorrection rate. The effects of botulinum toxin type A chemodenervation were better for relatively small angle and in partially accommodative ET than nonaccommodative one. But further study with more cases is needed.
