Analysis of serotype and drug resistance of pathogenic bacterium in bacillary dysentery
- VernacularTitle:细菌性痢疾病原菌血清分型及耐药性分析
- Author:
Weizhi HUANG
;
Shuying LI
- Publication Type:Journal Article
- Keywords:
Dysentery;
Shigella;
Serotyping;
Drug resistance,Bacterial
- From:
International Journal of Laboratory Medicine
2008;29(10):873-874,877
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the serotype and drug resistance of pathogenic bacterium in bacillary dysentery in our region, in order to provide evidence for prevention and control of bacillary dysentery. Methods 1 617 cases of stoli samples were collected from outpatients and inpatients with diarrhea. Bacterium isolation, cultivation and biochemical identification, serotyping and drug sensitive test were carried out. Results 165 strains of shigella were isolated, among which 88 strains were S. flexneri, 40 strains were S. sonnei, 21 strains were S. boydii and 16 strains were S. dysenteriae. 13 se-rotypes and subtypes were detected, serotype 2a of S. flexneri mostly. The total susceptibility rate of snigella was highest to nalidixic acid (more than 90%), followed by that to ampicillin, rifamoin, tet-racycline, trimoxazole (70. 0%-87.5%). The susceptibility rate to norfloxacin was 20. 5%-31.3%, and lower susceptibility rate (2.5%-6. 8%) was found to eefotaxime, gentamicin and eiprofloxacin. Conclusion The main serotype of bacillary dysentery was serotype 2a of S. flexneri in our region, then S. sonnei. The susceptibility of snigella to antibiotics is increasing, so drug susceptibility test should be performed periodically.
