Analysis on resistance pattern of 88 strains of isoniazid-resistant Mycobacteria
10.3760/cma.j.issn.1673-4130.2009.11.007
- VernacularTitle:88株耐异烟肼分支杆菌耐药模式分析
- Author:
Litao YANG
;
Xueqin YUAN
- Publication Type:Journal Article
- Keywords:
Isoniazid;
Mycobacterium tuberculosis;
Drug resistance,bacterial;
Microbial sensitivity tests
- From:
International Journal of Laboratory Medicine
2009;30(11):1058-1059,1062
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the multi-resistance pattern of 88 strains of isoniazid-resistant Mycobacteria in recent years,so as to provide reference for prevention and treatment of tuberculosis.Methods Absolute concentration method was applied to performing drug susceptibility test for 181 isolates of Mycobacteria to 10 kinds of antitubercuIosis drugs. Results The primary resistance rate was 19.3%,and the acquired drug resistance rate Was 55.8%.The percentage of isoniazid-or double resistant-Mycobacteria was 37.6%.The Mycobacterium which was resistant to three or above drugs accounted for 85.2 %.Conclusion The majority of isoniazid-resistant Mycobacterium is a multi-resistant strain,which should be thought highly in prevention and treatment of tuberculosis to control or reduce the initial and acquired resistance rates.
