The hemostatic effect of emergent hemostasis patch
- VernacularTitle:急救止血敷片的止血作用
- Author:
Yongxiao CAO
;
Zhao MA
;
Shaofei ZHU
;
Jing LIU
;
Tong ZHU
- Publication Type:Journal Article
- Keywords:
emergent hemostasis patch;
coagulation;
hemostasis;
femoral artery
- From:Journal of Xi'an Jiaotong University(Medical Sciences)
2010;31(2):169-171,189
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the hemostatic effect of emergent hemostasis patch (EHP). Methods The coagulation time was studied with tube method in vitro. Hemostasis was studied with femoral artery hemorrhage models of rats and dogs as well as rabbit hepatorrhexis model in vivo. Results The clotting time of EHP of high, medium and low concentrations was (4.9±1.3)min, (5.7±1.8)min and (5.8±1.3)min, respectively, which was significantly lower than that of control (14.4±1.6)min in vitro. In femoral hemorrhage models of rats and dogs, the duration and amount of bleeding in EHP of high, medium and low doses were significantly decreased compared with those in the PVF sponge group (P<0.01 or P<0.05). The results of rabbit hepatorrhexis experiment showed that EHP of three doses obviously decreased the hemostatic time and blood loss compared with PVF sponge group (P<0.01). Conclusion EHP can shorten coagulation time and bleeding time, and reduce bleeding amount.
