Peritumoral Diffusion Tensor Imaging of High Grade Astrocytoma and Metastasis

VernacularTitle:磁共振弥散张量成像在脑高级别星形细胞瘤和转移瘤瘤周实质区的诊断价值
Author: Lei SHI ; Hui ZHANG ; Guoliang SHAO ; Yanping YU ; Weiqiang PANG
Publication Type:Journal Article
Keywords: brain; MR imaging; diffusion tensor imaging(DTI); astrocytoma; metastasis
From: Journal of Practical Radiology 2010;26(4):478-480,484
CountryChina
Language:Chinese
Abstract: Objective To study the value and clinical significance of diffusion tensor imaging(DTI)in differentiating high-grade astrocytomas and solitary metastatic tumors of brain.Methods 16 patients with intracranial solitary metastasis and 25 patients with high-grade astrocytoma confirmed pathologically were examined with MR DTI.Mean diffusivity(MD)and fractional anisotropy(FA)were measured in the regions of interest(ROI)of peritumor and cerebral parenchyma of the normal side on DTL Fiber tractography was reconstructed and the encountered patterns of tumor-related alteration to cerebral white matter were observed.Results The peritumor were all depicted as hyperintense or isointense signals on DTI.The FA values were 0.227±0.05 and 0.169±0.07 in the peritumor of high-grade astrocytoma and metastasis respectively,which was of significant difference(P＜0.05).Furthermore,fiber tractography could display the course of white matter tracts in three-dimensional space.Conclusion DTI may be help to differential diagnosis of solitary metastasis and high-grade astrocytoma in clinical practice.