Development of the construction and delivery of siRNA
- VernacularTitle:siRNA构建及转运方法研究进展
- Author:
Baojun WEI
;
Jinming LI
- Publication Type:Journal Article
- Keywords:
Small interfering RNA:Construction:Delivery
- From:
International Journal of Biomedical Engineering
2008;31(2):-
- CountryChina
- Language:Chinese
-
Abstract:
RNA interference(RNAi)is a post-transcriptional gene-silencing phenomenon which is triggered by double-stranded RNA(dsRNA).Attempts age being made to exploit RNAi in a clinical setting.However,before RNAi can be exploited as therepeutically,several obstacles must be overcome such as the efficient and safe delivery of siRNA into target tissues and cells.Any usefull delivery method should be desinged to target siRNA.
