The significance of anti-endothelial cell antibody AECA in Behcet's disease
- VernacularTitle:间接免疫荧光法检测抗内皮细胞抗体在白塞病诊断中的意义
- Author:
Rulin JIA
;
Ru LI
;
Ongzhe LI
;
Liang LU
;
Yuan JIA
;
Zhanguo LI
- Publication Type:Journal Article
- Keywords:
Behcet's syndrome;
Fluorescent antibody technique,indirect;
Anti-endothelial cellantibody
- From:
Chinese Journal of Rheumatology
2008;12(10):688-690,插2
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the significance of anti-endothelial cell antibody (AECA) and the correlation between AECA and clinical features of Behcet's disease (BD). Methods AECA was detected in 73 BD, 60 SLE, 35 SSc, 30 RA, 62 systemic vasculitis patients and 40 health controls by indirect immunofluorescence analysis in which the endothelial cells from umbilical vein were used as the substrate. Results Higher frequency of AECA was found in BD (54.8%) with the specificity of 87.2%, compared to those in SLE (8%), SSc (9%), RA (10%), systemic vasculitis (27%) and healthy controls (2%, P
