The impaired insulin secretion and β-cell failure in type 2 diabetes
10.3760/cma.j.issn.1000-6699.2009.01.048
- VernacularTitle:胰岛素分泌受损与2型糖尿病β细胞的衰竭
- Author:
Xiaohui GUO
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
β-cell
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(2):-
- CountryChina
- Language:Chinese
-
Abstract:
Type 2 diabetes is a heterogeneous disorder caused by concomitant impairment of β-cell dysfunction,the hallmark of which is a series of abnormalities of histology and pathophysiology.The impairment of insulin secretion of type 2 diabetes is related to insulin deficiency and abnormal β-cell secretion.The progressive deterioration in β-cell function and mags in type 2 diabetes are the driving forces for the disease progression.
