Analysis of a case of systemic sclerosis complicated by noncirrhotic portal hypertension and literature review
10.3760/cma.j.issn.1007-7480.2010.02.014
- VernacularTitle:系统性硬化症合并非肝硬化性门静脉高压症一例并文献复习
- Author:
Junwei CHEN
;
Shaoran ZHANG
;
Xiaoxiang XIAN
;
Zheng ZHANG
;
Yufeng YANG
;
Guozhu CHE
;
Huiping SUN
;
Zhu CHEN
;
Xiaofeng LI
- Publication Type:Journal Article
- Keywords:
Sclerosis;
Hypertension,portal;
Retrospective studies
- From:
Chinese Journal of Rheumatology
2010;14(2):115-118,后插一
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the rheumatologists' understanding of noncirrhotic portal hypertension.MethodsA case of systemic sclerosis complicated by noncirrhotic portal hypertension was reported and the related literatures were reviewed.Results A 51-year-old female who had been diagnosed as systemic sclerosis presented clinically with an chronic onset of portal hypertension.She also had pancytopenia,splenomegaly,and significant esophageal varices.Liver function tests were normal.Hepatitis viral serology was negative.Ultrasound scan of liver revealed no focal lesion.ACT scan confirmed the absence of portal vein thrombosis.Taking into account the above evaluation we concluded that the patient had systemic sclerosis and noncirrhotic portal hypertension.The patient was on prednisolone and immunosuppressant and the condition was well.Conclusion Noncirrhotic portal hypertension complicated by autoimmune disease,especially SSC,is very poor,characteriged by significant portal hypertension as well as histological evidence that cirrhosis is absent.Rheumatilogist should pay attention to it.
