DNA microarray technology and its application advances in articular cartilage research
10.3760/cma.j.issn.1673-4181.2009.06.010
- VernacularTitle:基因芯片技术在关节软骨研究中的应用进展
- Author:
Xuhong XUE
;
Qixin ZHENG
;
Hongbin WU
- Publication Type:Journal Article
- Keywords:
DNA microarry;
Articular cartilage;
Formation and development;
Injury and repair;
Biological characteristics
- From:
International Journal of Biomedical Engineering
2009;32(6):359-362,370
- CountryChina
- Language:Chinese
-
Abstract:
DNA microarray generally refers to gene chips. Its basic principle is that a large number of oligonucleotide molecules were fixed on the support, and then hybridized with the labeled samples, and then the chip hybridization signal strength was scanned to determine the number of target in the samples. Gene chips can trace the nucleotide sequence in the samples for testing and analyzing. Its characteristics of high-throughput,rapid and parallel acquisition of biological information are better than that of other traditional gene detection technology. It has been widely used in various fields of medical research. This article reviews the application of DNA microarray technology in the study of orthopedics including biological characteristics, formation and development,injury and repair, degeneration and regeneration of articular cartilage.
