Resistance mechanisms to antibiotic in vitro in mycoplasma pneumoniae
10.3760/cma.j.issn.1673-4408.2010.01.026
- VernacularTitle:肺炎支原体体外诱导抗生素耐药及其机制
- Author:
Dawei SHI
;
Deli XIN
- Publication Type:Journal Article
- Keywords:
Pneumoniae;
Mycoplasma pneumoniae;
Drug resistance;
Induction,;
Antibiotics
- From:
International Journal of Pediatrics
2010;37(1):82-83,87
- CountryChina
- Language:Chinese
-
Abstract:
Mycoplasma pneumoniae(MP) is a common pathogen found in respiratory tract infections of children and is susceptible to macrolides, tetracycline, aminogly-cosides, and quinoloines . Of all these antibiotics, macrolides is the frist choice for children. However,in recent years, strains which are resistant to common drugs have been selected in vitro and isolated from patients Point mutation at antibitics target site of these 8trains is one of the molecular mechanisms.The study of MP resistance can provide theoretical guidance for rational choice of antibiotics and application.
