The relationship between the expressions of glucose transporter protein-1,vascular endothelial growth factor in pancreatic cancer and the clinical indicators
10.3760/cma.j.issn.1673-4203.2010.07.009
- VernacularTitle:VEGF和Glut-1在胰腺癌中表达及与临床指标的关系
- Author:
Bing YANG
;
Jiang CHEN
;
Chunsheng ZHENG
- Publication Type:Journal Article
- Keywords:
Pancreatic cancer;
Glucose transporter protein-1;
Vascular endothelialgrowth factor
- From:
International Journal of Surgery
2010;37(7):455-457,封3
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the expressions of glucose transporter protein-1 ,vascular endothelial growth factor in pancreatic cancer and the clinical indicators.Methods Im-munohistochemical staining was done in glucose transporter protein-1,vascular endothelial growth factor in pancreatic cancer and normal pancreas tissues.Results Glucose transporter protein-1,vascular endothelial growth factor of pancreatic cancer were expressed higher than that in normal tissue.The difference was statistically significant(P < 0.05).VEGF expression was related with lymph node metastasis,not with tumor grade,clinical stage(P<0.05).Glut-1 expression was related with tumor size,clinical stage and lymph node metastasis,not with pathological grading(P< 0.05).Conclusions Glucose transporter protein-1 ,vascular endothelial growth factor in pancreatic cancer are highly expressed .Both of them may participate in occurrence and development in pancreatic cancer.
