lmmunohistochemical studies and HRP retrograde tracing of cerebral neocortical transplantation in rats
- VernacularTitle:大鼠大脑新皮质组织移植后免疫组织化学及辣根过氧化物酶追踪的研究
- Author:
Jian HUANG
;
Kelan WU
;
Cuihuan WU
- Publication Type:Journal Article
- Keywords:
Brain/transplantation;
Embryo;
Cerebral cortex;
Neural conduction
- From:
Chinese Journal of Organ Transplantation
1997;18(1):36-38,后插一
- CountryChina
- Language:Chinese
-
Abstract:
The fetal neocortieal transplant(E15～17 days of gestation) of Wistar rats was grafted to the corresponding neocortical region of young rats of same strain.The immunohis-tochemical study and horseradish peroxidase(HRP) retrograde tracing were performed on the 7th,15th,30th, 60th,150th day after transplantation.The results showed that most grafted neurons survived,grew,differentiated and matured.The morphology of neurons was similar to the struc-ture of the neocortical neurons of host brain;integration of varying degree at the interface and reciprocal connection between graft and host brain tissue were established.
