Iron metabolism and neonatal hypoxic-ischemic encephalopathy
10.3760/cma.j.issn.1673-4408.2010.06.018
- VernacularTitle:铁代谢与新生儿缺氧缺血性脑病
- Author:
Haibo HUANG
- Publication Type:Journal Article
- Keywords:
Iron metabolism;
Free radical;
Hypoxic-ischemic encephalopathy;
Neonate
- From:
International Journal of Pediatrics
2010;37(6):604-605,609
- CountryChina
- Language:Chinese
-
Abstract:
Iron homeostasis is essential for the maintenance of the body. Iron transports oxygen and electron, and participates in the synthesis of neurotransmitters and myelin. However, iron overload in the body is harmful. In recent years studies have found iron deposition would be poisoned significantly, particularly in the central nervous system tissues and nerve cells, which will cause pathological changes of central nervous system.This paper describes the iron and cycled iron changes in hypoxic-ischemic brain, abnormal iron metabolism and mechanisms of HIE.
