The implementation of speckle tracking imaging technology on functional assessment of regional myocardial contraction in patients with systemic lupus erythematosus
10.3760/cma.j.issn.1007-7480.2011.02.007
- VernacularTitle:超声斑点追踪技术对系统性红斑狼疮患者局部心肌收缩功能的评价
- Author:
Yingyan QIAO
;
Chenggong LEI
;
Yinlin DUAN
;
Fang LU
;
Ze WANG
;
Caihong WANG
;
Jiu ZHANG
;
Hongshan MA
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Speckle tracking imaging;
Automated functional imaging software;
Systolic peak strain
- From:
Chinese Journal of Rheumatology
2011;15(2):97-100,后插2
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the vaIue of speckle tracking imaging (STI) in quantifying the regional myocardial strain in systemic lupus erythematosus (SLE) group.Methods ① Sixty subjects were divided into SLE group and normal group.High frame rate two-dimensional images were recorded from the apical two-chamber view,long-axis view and four-chamber view of the left ventricle (LV).Peak systolic strain of each view of 18 segments were measured by automated functional imaging (AFI) software of 2-DSE.All parameters were compared between the two groups.② Twenty cases were randomly taken from the normal group.The same observer at different times and two observers measure the strain of left ventricular respectively.The results of the measurement between the two groups were compared with unpaired t test and its relevance was analyzed using Pearson's correlation analysis.ResultsLeft ventricular two-dimensional longitudinal strain gradually increased from the base to apex in the normal group.There were statistically differences between the apical segments and the basal,middle segments of every left ventricular wall (P＜0.05).The same wall segment time to peak myocardial systolic peak strain was consistent.Left ventricular two-dimensional longitudinal strain gradually increased from the base to apex in the SLE group,except for the anterio-septal and anterior wall [ (-18.7±4.2)％,(-16.3±9.4)％,(-18.1±10.5)％ vs (-19.0±9.0)％,(-18.6±7.9)％,(-17.7±1.4)％ ].There was no statistically significant difference between the apical segments and the basal,middle segments of every left ventricular wall(P＞0.05).All parameters of S were significantly higher in the normal group than those of the SLE group.The difference was statistically signoficant (P＜0.05).The time to peak systolic peak strain of every segments was not consistent.The results from the same observer at different times and peak systolic myocardial strain measurements by the two observers were correlated well(P＜0.01).Conclusion The myocardial function assessment by STI technology in the SLE patients is significantly different from that of the normal control:SLE patients with left ventricular myocardial damage can be manifested as reduced regional myocardial systolic peak strain.
