The clinical study of gamma knife in dose fraction treatment of brain gliomas
- VernacularTitle:伽玛刀剂量分割治疗脑深部胶质瘤的临床研究
- Author:
Pingping YAN
;
Fucheng ZHANG
;
Baolai LIU
- Publication Type:Journal Article
- Keywords:
Glioma;
Radiosurgery
- From:
Cancer Research and Clinic
2007;19(z1):45-46,50
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the dose fraction of gamma knife treatment brain deep larger glioma clinical efficacy.Methods To adopt rotating gamma knife in dose fraction treatment of brain deep larger(d>3 cm),64 cases of gliomas,were installed stereotactic head frame can repeat accessories,for a day,for two consecutive days to five,each around 5-10 Gy for each treatment,fixed the first-place after the removal,the next treatment repeat.ReslIlts After 6 to 24 months of follow-up was 57 patients,complete response(CR)in 8 cases,partial response(PR)in 29 cases,the total efficiency of 64.9%,no change(NC)in 14 cases,clinical benefit rate of 83.4%,progressive disease(PD)in 6 cases.Brain edema response after treatment was the major side effects.Conclusion For deep larger brain glioma,dose fraction of gamma knife treatment was clearly effective recently,it could ease symptoms and improve quality of life.