Clinical study of whole course accelerated fractionation radiotherapy for 126 patients with esophageal carcinoma
- VernacularTitle:全程超分割放射治疗食管癌126例
- Author:
Lianxing LIN
;
Zhiyuan XU
;
Yixuan LI
;
Chunyu LIANG
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms/radiotherapy;
Dose fractionation;
Prognosis
- From:
Cancer Research and Clinic
2008;20(9):618-619,622
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic effects of whole course hyperfractionation radiotherapy for esophageal carcinoma. Methods Form January 2000 to December 2001,126 patients with esophageal carcinoma were treated by whole course hyperfractionation radiotherapy(120～140 cGy per fraction, 2 times per day, to a total dose of 6400～7400 cGy) in our department. Results The short-term effective rate was 99.21%. The 1, 2 and 5 year survival rate was 61.11%, 41.27%, 23.02% and the median survival time was 1.29 years. The 1, 2 and 5 year disease-free survival rates was 57.94%, 38.10%, 19.84% and the median disease-free survival time was 1.16 years. Conclusion It is promising of whole course hyperfractionation radiotherapy for esophageal carcinoma. But it must be validated by the large-scale clinical trials.
