A Case of Drug Induced Interstitial Pneumonitis by Gemcitabine.
10.4046/trd.2004.56.3.315
- Author:
Sung Soon LEE
1
;
Cho Rom HAM
;
Jae Yong CHIN
;
Hye Ran LEE
;
Su Young KIM
;
Mi Young KIM
;
Hyun Kyung LEE
;
Hyuk Pyo LEE
;
Ho Kee YUM
;
Soo Jeon CHOI
Author Information
1. Department of Internal Medicine, Inje University, Medical School, Korea.
- Publication Type:Case Report
- Keywords:
Gemcitabine;
Pulmonary infiltrates;
Corticosteroid therapy;
Capillary leak syndrome
- MeSH:
Breast;
Bronchial Spasm;
Capillary Leak Syndrome;
Dyspnea;
Glass;
Humans;
Lung;
Lung Diseases, Interstitial*;
Prednisolone
- From:Tuberculosis and Respiratory Diseases
2004;56(3):315-320
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Gemcitabine is an effective newly developed chemotherapeutic agent, which is increasingly being used to treat non-small cell lung, ovarian and breast cancers. Pulmonary toxicity is usually self-limiting mild dyspnea, bronchospasm, but severe pulmonary toxicity is rarely reported. Herein, we report drug induced interstitial lung disease associated with gemcitabine treatment. High resolution computerized tomogram (HRCT) showed an increased ground glass opacity and thickened septal lines. The patient showed a rapid good response with prednisolone treatment.
