Integron-mediated Antibiotic Multiresistance in Acinetobacter baumannii Clinical Isolates
- VernacularTitle:关于整合子在鲍氏不动杆菌多药耐药性中的作用
- Author:
Jingping ZHANG
;
Bo ZHAO
;
Minghong LI
;
Wan ZHU
;
Baiyi CHEN
- Publication Type:Journal Article
- Keywords:
Acinetobacter baummanii;
Drug-resistance;
Integron
- From:
Chinese Journal of Nosocomiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To determine the category of gene cassettes in type 1 integrons of multi-resistant Acinetobacter baumannii from Shenyang.METHODS Fifty clinical isolates were collected from the First Affiliated Hospital of China Medical University and K-B test was used to determine the susceptibility and the results were read based on Clinical and Laboratory Standards Institute(CLSI) of the USA.PCR was used to detect the existance of integron,and DNA sequencing was also required.RESULTS There are thirty-two isolates positive for integron.Sequencing analysis showed the integrons carried two different known genes(arr-3 and aacA4).CONCLUSIONS The results show the potential risk of integron dissemination among different strains of A.baumannii.