Combined examination of 64-slice spiral computed tomography and inflammatory cytokines in the detection of vulnerable plaque of acute coronary syndrome
- VernacularTitle:64层螺旋CT联合炎症因子检测急性冠状动脉综合征患者易损斑块的相关研究
- Author:
Lixia YANG
;
Jialin ZHENG
;
Rui YAN
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Tomography,spiral computed;
C-reactive protein;
Matrix metalloproteinases
- From:
Chinese Journal of Interventional Cardiology
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of 64-slice spiral computed tomography combined with hs-CRP and MMP-9 to detect the vulnerable plaque of acute coronary syndrome.Methods Seventy-two patients with coronary heart disease were included and among them,43 patients were diagnosed as ACS and the other 29 patients diagnosed as stable angina group(SAP).All patients underwent 64-slice spiral computed tomography coronary artery imaging and examination of plasma hs-CRP and MMP-9 concentration.All patients underwent selective coronary angiography.Another 25 cases who underwent coronary angiography were included in the control group.Results The incidence of soft plaque was higher in the ACS group than in the SAP group(24 cases vs 4 cases,P=0.001).Compared with the control group,levels of hs-CRP and MMP-9 in the ACS group and the SAP group were both significantly higher(all P
