Comparison of curative effects between domestic and imported monosialotetrahexosyl ganglioside sodium on neonatal hypoxic ischemic encephalopathy
- VernacularTitle:国产及进口单唾液酸四己糖神经节苷脂治疗新生儿缺氧缺血性脑病疗效比较
- Author:
Dalin FU
;
Yue ZHANG
;
Jian TANG
- Publication Type:Journal Article
- Keywords:
neonatal hypoxic ischemic encephalopathy;
monosialotetrahexosyl ganglioside sodium
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the curative effects between domestic and imported monosialotetrahexosyl ganglioside sodium (GM 1) on neonatal hypoxic ischemic encephalopathy(HIE).Methods 104 neonates with HIE were randomly divided into Shenjie group(domestic GM 1,53 cases )and Pharma group (imported GM 1,51 cases).At the basic of conventional therapy,the two groups received domestic or imported GM 1 20 mg /d intravenous infusion for 7～ 28 d,rspectively.The curative effects and adverse reaction were observed.Results The total effective rates in Shenjie group and Pharma group were 98.11% and 88.24%,respectively.There was no significant difference between the two groups.While,there was no obvious adverse reaction in the two groups.Conclusion Both the domestic and imported GM 1 have the same good curative effects and safety on neonatal HIE.
