Effect of Lovastatin on carotid atherosclerotic plaques, levels of blood lipid and serum C-reactive protein
- VernacularTitle:洛伐他汀对颈动脉粥样硬化斑块、血脂及血清C-反应蛋白水平的影响
- Author:
Jijun YIN
;
Feng LIN
;
Gaolin WANG
- Publication Type:Journal Article
- Keywords:
Lovastatin;
cerebral infarction;
atherosclerosis;
blood-lipid;
C-reactive protein
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Lovastatin on carotid atherosclerotic plaque(CAP),levels of blood lipid and serum C-reactive protein(CRP) in patients with cerebral infarction(CI).Methods 120 CI patients with CAP were randomly divided into Lovastatin group and control group.At the basic of low fit diet for the two groups,Lovastatin was taken with 20 mg once a day for 6 months in Lovastatin group.Then,the changes of paque score,the levels of CRP and blood-lipid were observed 8 weeks and 6 months after treatment.Results (1)6 months later,the plaque score(4.20?3.77) in the Lovastatin group was significantly lower than pro-treatment(4.77?2.31)and the control group(6.86?1.89) (all P
