Distribution of Pathogens and Characteristics of Drug Resistance in Intensive Care Unit 2007-2008
- VernacularTitle:2007-2008年重症监护病房病原菌分布及耐药性分析
- Author:
Shusheng ZHOU
;
Bao LIU
;
Linlin ZHANG
;
Jinsong ZHAO
;
Xiaolan GAO
;
Yuanyuan DAI
- Publication Type:Journal Article
- Keywords:
ICU;
Pathogen;
Drug resistance
- From:
Chinese Journal of Nosocomiology
2009;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the distribution of pathogenic bacteria and the status of drug resistance in intensive care unit(ICU) of Anhui Provinceical Hospital,to provide reference for rational use of the antibiotics in clinical practice and effective control of hospital infection.METHODS From Jan 2007 to Dec 2008,a total of 873 clinical isolates were collected from different samples of infective patients in ICU,drug sensitivity test was conducted based on disk diffusion testing(K-B),to analyze the drug resistance of the pathogenic bacteria.RESULTS The highest isolating rate came from the sample of respiratory tract,which was 68.96%.Among 873 clinical isolates,Gram-negative bacilli and Gram-positive cocci accounted for 65.95% and 19.22%,respectively.Gram positive cocci rised obviously in 2008 compared to 2007.The rate of bacterial drug resistance was relatively high,meticillin-resistant Staphylococcus aureus(MRSA) detection rate was 56.58%;The detection rates Escherichia coli and Klebsiella ESBLs were 75.00% and 57.41%.CONCLUSIONS There is a higher rate of infection for ICU patients,and the condition of drug resistance is serious.To strengthen the pathogen distribution and drug resistance monitoring is of great guiding significance for rational clinical use of drug,reducing multi-drug resistance and nosocomial infection control.
