Study on drug addiction ability of cemedex in experiments with white mice
- Author:
Huang -- Renbin
- Publication Type:Journal Article
- Keywords:
Addiction
- MeSH:
Substance-Related Disorders;
Mice;
Animal Experimentation
- From:Journal of Practical Medicine
2005;0(6):78-79
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Aims of this study are investigating whether Cedemex could cause addiction and evaluating the safety level of this drug. Researchers used the methods of detoxication promoting or drug hunger stimulating and natural detoxication to evaluate the ability to cause addiction of Cedemex for white mice. Result: White mice were given continuously Cedemex in 9 days, and then they were given Nalotone to stimulate the drug hunger, however, there was not any sign of drug hunger and weight decrease. The natural detoxication group was given Cedemex with gradually increasing dose (2g/kg, 4g/kg, and 8g/kg body weight), drug is pumped into stomach twice a day and continuously in 9 days,, each kind of dose is given in 3 days. After stop giving Cedemex, there was not sign of drug hunger and weight decrease. Therefore, Cedemex does not have the cause drug addiction and has high safety level.
