Analysis of Pathogens and Risk Factors of Ventilator-associated Pneumonia in Intensive Care Unit
- VernacularTitle:重症监护病房呼吸机相关肺炎病原学及危险因素分析
- Author:
Qian LI
;
Renhua SUN
;
Minhua CHEN
- Publication Type:Journal Article
- Keywords:
Intensive care unit;
Ventilator-associated pneumonia;
Pathogens;
Antibiotics resistance;
Risk factors
- From:
Chinese Journal of Nosocomiology
2009;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate pathogens,drug resistance and the risk factors of ventilator-associated pneumonia(VAP) in our intensive care unit(ICU).METHODS Spetum samples collected from the low respiratory trachea of the VAP patients from July 2008 to May 2009 in ICU received bacterial culture and antibiotics sensitive test.The risk factors related to VAP were identified and evaluated with Chi-square test.RESULTS 82 strains of pathogens had been isolated by culture and most of which were Gram negative bacilli(69.51%).The other pathogens included Gram positive cocci(25.61%) and fungi(4.88%).The most common pathogens were Acinetobacter calcoaceticus-baumannii,Staphylococcus aureus and Pseudomonas aeruginosa.Most of the Gram negative bacilli were highly resistant to many kind of antibiotics,especially Acinetobacter calcoaceticus-baumannii.77.8% of S.aureus were Meticillin-resistant S.aureus(MRSA),and all sensitive to Vancomycin.The duration of mechanical ventilation≥5 days,age≥65 years,gastric acid secretion inhibitor(GASI) therapy and albumen
