Teicoplanin Treatment of Severe Community-acquired pneumonia among Elderly:A Retrospective Analysis
- VernacularTitle:替考拉宁经验治疗老年重症社区获得性肺炎降低治疗失败率的回顾分析
- Author:
Yiqun XIE
;
Hongbo DENG
;
Ping ZHANG
;
Youyuan LI
;
Yi ZENG
;
Yuxin YI
- Publication Type:Journal Article
- Keywords:
Community-acquired pneumonia;
Elderly;
Teicoplanin;
Gram-positive bacterium
- From:
Chinese Journal of Nosocomiology
2009;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the rationality of teicoplanin for the empirical treatment of severe community-acquired pneumonia(CAP) in the aged.METHODS Totally 179 hospitalized cases of severe CAP were enrolled and divided into two groups,teicoplanin treatment group(67 cases) and non-teicoplanin treatment group(112 cases),whose clinical data and antibiotic empirical treatment were analyzed respectively,compared their PSI scores and clinical outcomes after 5 day′s therapy.RESULTS The PSI scores had no significant difference of two groups.The total treatment failure rate in teicoplanin treatment group was 23.9%,lower than that in non-teicoplanin treatment group.The treatment failure rate of teicoplanin combining the third generation cephalosporin treatment cases was 19.4%,lower than that in single use of cephalosporin(50.0%),also less than that in the cases of cephalosporin combining other antibiotics therapy,which accounted for 32.1%.CONCLUSIONS The use of teicoplanin may reduce treatment failure rate of severe CAP among aged.
