Clinical Distribution and Drug Resistance Analysis of 60 Stenotrophomonas maltophilia Isolates
- VernacularTitle:60株嗜麦芽寡养单胞菌的临床分布与耐药性分析
- Author:
Jun MENG
;
Sufang GUO
;
Yongmei ZHANG
;
Quan FU
- Publication Type:Journal Article
- Keywords:
Stenotrophomonas maltophilia;
Drug resistance;
Antibiotic
- From:
Chinese Journal of Nosocomiology
2009;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the clinical distribution and drug resistance status of Stenotrophomonas maltophilia and provide clinical guidance for treatment.METHODS Sixty clinical isolates of S.maltophilia were identified with GNI+ cards of VITEK-32.Drug sensitivitiy were detected by Kirby-Bauer disc diffusion method.The data were analyzed by WHONET5.3 software.RESULTS Thirty-eight strains were isolated from sputum(63.3%).Infection caused by S.maltophilia mainly occurred at the departments of respiratory diseases,ICU,old cadre,et al.Sixty isolates of S.maltophilia were highly resistant to imipenem,aminoglycosides and most of ?-lactam antibiotic,but showed the lowest resistance rate(16.7%) to SMZ/TMP.Then resistance rate of S.maltophilia to minocycline,levofloxacin,cefoperazone/sulbactam,piperacillin/tazobactam,and ticarcillin/clavulanic acid was 18.3%,20.0%,21.7%,25.0% and 30.0%,respectively.CONCLUSIONS The drug resistance of S.maltophilia is extremely severe.Among different areas of china the drug resistance is obviously different.Treatment based on drug susceptibility test should be adapted as soon as possible.
