Distribution and Drug-resistance of Staphylococcus aureus in Intensive Care Unit
- VernacularTitle:重症监护病房患者感染葡萄球菌属的分布及耐药谱型研究
- Author:
Jingfang YANG
;
Yue WANG
;
Jihong LI
- Publication Type:Journal Article
- Keywords:
Meticillin-resistant Staphylococcus aureus;
Drug resistance;
Preventive measures
- From:
Chinese Journal of Nosocomiology
2009;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the resistance of Staphylococcus aureus,includ MRSA and MSSA,to antimicrobial agents in intensive care unit(ICU),and to provide basis for clinical therapy.METHODS K-B disk diffusion method was used to determine the drug susceptibility of 171 strains of S.aureus,and meticillin-resistant S.aureus(MRSA) was detected by using the disk diffusion method according to NCCLS/CLSI.RESULTS In ICU,S.aureus was isolated mostly from the respiratory tract,urine tract and blood.MRSA made up 57.89%.For MRSA and MSSA,no resistance against vancomycin and norvancomycin was observed.The resistance rates of MRSA to other agents were as follows: chloramphenicol 20.45%,and minocycline 20.45%.While the resistance rates of MSSA to other agents were as follows:cefazolin 6.25%,and amikacin 6.25%,minocycline 9.38%.CONCLUSIONS MRSA shows the multidrug resistance.Pathogenic monitoring,keeping the patients apart,rational utilization of antibiotics,medical facility sterilization strictly and intensive hand hygiene are very important to prevent MRSA infection.
