Antibiotic Resistance Analysis in Nosocomial Infections with Acinetobacter baumannii from Lower Respiratory Tract in ICU
- VernacularTitle:重症监护病房下呼吸道医院感染鲍氏不动杆菌的耐药性分析
- Author:
Pingan ZHANG
;
Chong WU
;
Jinling SHI
;
Xuan CAI
;
Duanyang SUN
;
Shaohua PENG
- Publication Type:Journal Article
- Keywords:
Intensive care unit(ICU);
Lower respiratory tract;
Nosocomial infections;
Acinetobacter baumannii;
Antibiotic resistance
- From:
Chinese Journal of Nosocomiology
2009;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate antibiotic resistance in nosocomial infections with Acinetobacter baumannii from lower respiratory tract in the intensive care unit(ICU) and guide clinically rational use of drug.METHODS Antibiotics susceptibility tests in 109 clinical isolates of A.baumannii from lower respiratiory tract were performed by K-B disk diffusion method.The results were judged according to CLSI 2007.As controls,standard strain was used simultaneously.RESULTS The sensitivity rate to cefoperazone/sulbactam was the highest,arriving at 77.1% and followed by imipenem(57.8%) and meropenem(54.9%).The other antibiotics were below 50.0%,generally.The serious cross-resistance phenomenon was in present.Pan-resistant strains had been detected.CONCLUSIONS The drug-resistant status in nosocomial infections with A.baumannii from lower respiratory tract in ICU is very serious.We should continue to strengthen the monitoring of the antibiotic resistance and prevent the outbreak epidemics of drug resistant strains in ICU.
