Cancer stem cells and stem cells:Source,differentiation and their correlation
- VernacularTitle:肿瘤干细胞与干细胞:来源、分化及其相关性
- Author:
Bin LING
;
Jing CHEN
;
Jie SUN
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(49):-
- CountryChina
- Language:Chinese
-
Abstract:
Cancer stem cells are a new field with the gradual deep understanding of the stem cell research.Although its history is not long,the rapid development showed a good potential prospect.The existence of cancer stem cells and its use as tumor formation,growth and metastasis-based approach has been widely recognized.In theory,cancer stem cells derived from normal stem cells can transform.Cancer-causing factors can also be derived from the dedifferentiation induced cells.Because it contains all-round,multi-and single stem cell,with the proliferation and differentiation potential of different directions,it is possible to explain the heterogeneity of tumor cells,and reasons for hypoxic environment,anti-cancer drugs and radiation resilience.In this area,it has been made a lot of progress in recent years.However,there are still some problems to be solved.Such as the identification of cancer stem cells,biological function and mechanism.
