Proteomic analysis of ginsenoside-Rh2 on inhibition of human glioma cell line SHG-44
- VernacularTitle:人参皂甙Rh2对人脑恶性胶质瘤SHG-44细胞抗肿瘤作用的蛋白质组学分析
- Author:
Xinyu HONG
;
Jiayue CUI
;
Wenchen LI
;
Bo CHEN
;
Yinan LUO
- Publication Type:Journal Article
- Keywords:
panaxosides;
glioma;
proteomics
- From:
Journal of Jilin University(Medicine Edition)
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the mechanism of ginsenoside-Rh2(G-Rh2) on inhibition of glioma by identifying differential proteins with proteomic technique. Methods The total proteins were extracted from SHG-44 cells treated with 32 ?mol?L-1 G-Rh2 for 72 h and the cells in control group,then were subjected to two-dimensional gel electrophoresis.Only spots with a fold change equal or above 1.5 and P