Efficacy evaluation of aortic lymph node-positive patients with pancreatic and bile duct cancer after operation

VernacularTitle:腹主动脉旁淋巴结阳性的胰头及胆管癌患者术后疗效评估
Author: Bo REN
Publication Type:Journal Article
Keywords: Pancreatic Neoplasms; Lymph Node
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(23):3239-3240,后插2
CountryChina
Language:Chinese
Abstract: Objective To explore the clinicopathologic features and surgicalResultsof paraaortic node-positive periampullary adenocarcinoma. Methods101 patients underwent pancreatectomy with regional and paraaortic lymphadenectomy.Fifteen(15%)patients had histologically proven paraaortic lymph node disease. ResultsThe 15 patients included 9(26%)of 34 patients with pancreatic head carcinoma and 6(17%)of 36 patients with bile duct adenocarcinoma.All 15 patients had locally advanced tumor invading adjacent structures.The 1-,2-,and 3-year survival rates were 33%,27%,and 0%,with median survival of 12 months(range from 3 to 33months).In patients with pancreatic head carcinoma or bile duct adenocarcinoma,survival curve for those without paranortic lymph node metastasis was significantly better than those with involved paraaortic lymph nodes(P＜0.01). ConclusionWhen the paraaortic lymph nodes obtained from sampling biopsy were histologically positive,radical pancreatectomy with extended lymphatic and soft tissue clearance should be abandoned owing to poor outcome.