Study on synthesis on 7anpha-pregn-11beta, 17beta-diol-4-en-3-on-20-yne from 11beta-hydroxy-androstendion-3,17
- Author:
Luu Duc Huy
- Publication Type:Journal Article
- Keywords:
Synthesis, 7anpha -pregn-11beta, 17beta-diol-4-en-3-on-20-yne, 11beta-hydroxy-androstendion-3,17
- MeSH:
Pharmaceutical Preparations;
Pharmacology;
Androstenedione
- From:Pharmaceutical Journal
2004;34(11):19-21
- CountryViet Nam
- Language:Vietnamese
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Abstract:
From androst- 4,9(11)-dien-3,17-dion the synthesis of ethynylsteroid 17 alpha-pregn-11beta, 17-beta-diol-4-en-3-on20-yn was performed with a productivity of 68%. The 17 alpha-ethynylzition gave a productivity of 90%. The by product is 4% of 17 beta- ethynylization product. The product was identified by melting point, IR spectrum, proton magnetic resonance spectrum and mass spectrum
