Transfusion related acute lung injury occurred in HLA half-matched hematopoietic stem cell transplantation:a case report and literature review
- VernacularTitle:半相合造血干细胞移植中发生的输血相关急性肺损伤:1例病例报告附文献复习
- Author:
Dongfeng ZENG
;
Peiyan KONG
;
Xinghua CHEN
- Publication Type:Journal Article
- Keywords:
Transfusion related acute lung injury (TRALI);
HLA half-matched hematopoietic stem cell transplantation;
Blood products infusion
- From:
Chinese Journal of Blood Transfusion
2008;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To clarify the risk,treatment and preventive measurement of transfusion related acute lung injury (TRALI) occurred in HLA half-matched hematopoietic stem cell transplantation. Methods A case of TRALI occurred in HLA half-matched hematopoietic stem cell transplantation was analyzed,including the clinical characteristics,the laboratory and instrumental examination,the treatment measure and prognosis,and then the associated literature was reviewed.Results Owing to the blood products(fresh platelet) transfusion during transplantation,the patient got TRALI. And after active rescue,the patient eventually died due to the worsen condition.Conclusion The risk of TRALI is very high in HLA half-matched hematopoietic stem cell transplantation since the blood products transfusion is inevitable,so the effective and timely treatment and preventive measurement are necessary.
