Sampledrawing from animal models of allergic airway inflammation
- VernacularTitle:变应性气道炎症动物模型的实验取材
- Author:
Dingyuan XU
;
Yong ZHANG
;
Fei XUE
;
Junfeng JI
;
Zeqing LI
;
Bo WU
;
Qiupin WANG
- Publication Type:Journal Article
- Keywords:
Allergic inflammation;
Airway;
Sampledrawing
- From:
Journal of Medical Postgraduates
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Sampledrawing is an important procedure in the study of allergic airway inflammation.The authors investigate the methods of drawing samples from the animals with allergic airway inflammation.Methods: We included in this study 20 Guinea pigs,10 rats and 20 mice,which underwent trachea incision,followed by bronchoalveolar and rhinal lavage and collection of the lavage fluids.Then we collected blood samples via the heart from the guinea pigs and rats and via both the heart and the eyes from the mice,and obtained the tissues of the nasal cavities and lungs by different methods.Results: All the samples were satisfactorily obtained from the animals,and 80% of the bronchoalveolar and rhinal lavage fluids were collected.Conclusion: Different methods should be adopted to suit different sampledrawing from the animal models of allergic airway inflammation.
