On the cardiovascular effects of GLP-1 from recent studies
10.3760/cma.j.issn.1000-6699.2010.05.029
- VernacularTitle:从近期研究看GLP-1对心血管的作用
- Author:
Changyu PAN
- Publication Type:Journal Article
- Keywords:
Glucagon-like peptide-1;
Cardiovascular disease;
Liraglutide;
Diabetes mellitus,type 2
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(5):后插1-4
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular disease is the main cause of death in patients with type 2 diabetes. The protection of glucagon-like peptide-1 ( GLP-1 ) on endothelial function, ischemic myocardial damage, and heart failure have been reviewed. Based on the recently finished serial clinical studies, the effects that long-acting GLP-1 analogues liraglutide improved body weight, blood pressure, lipids, and other cardiovascular risk factors were discussed.