Comparison of Moxifloxacin and Cefuroxime Combined with Azithromycin for Patients with Community-acquired Pneumonia
- VernacularTitle:莫西沙星与头孢呋辛联用阿奇霉素治疗社区获得性肺炎的对照研究
- Author:
Weihua GAO
;
Kaisong WU
;
Yuhui LIN
;
Zhenshun CHEN
- Publication Type:Journal Article
- Keywords:
Moxifloxacin;
Cefuroxime;
Azithromycin;
Community-acquired pneumonia
- From:
Chinese Journal of Nosocomiology
2009;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the efficacy,the eradication rates of pathogens and safety of moxifloxacin in patients with community-acquired pneumonia(CAP) in comparison with therapy using a combination of cefuroxime plus azithromycin.METHODS Seventy eight patients with CAP were randomly divided into two groups:moxifloxacin alone and cefuroxime plus azithromycin,and the efficacy,the eradication rates of pathogens and the rates of side effects were observed.RESULTS From 40 patients in the moxifloxacin group,32 patients(80%) were clinically cured and 6 patients(15%)were improved.And from 38 patients in the cefuroxime plus azithromycin groups,30 patients(78.9%) were clinically cured and 5 patients(13.2%) were improved.The eradication rates of pathogens were 89% and 84%,respectively.And the rates of side effects were 7.5% and 7.9%,respectively.CONCLUSIONS There are no significant differences in the efficacy,the eradication rates of pathogens and safety between 2 groups in treating community-acquired pneumonia.
