Prowess in the study on induction of bone marrow stromal cells into mature functional neural cells
10.3760/cma.j.issn.1673-4181.2009.04.010
- VernacularTitle:骨髓基质干细胞向有功能性神经细胞诱导分化的研究进展
- Author:
Pengbin LI
;
Qizing ZHENG
- Publication Type:Journal Article
- Keywords:
Bone marrow stromal cells;
Neural cells;
Induction;
Functional characteristics
- From:
International Journal of Biomedical Engineering
2009;32(4):234-237,250
- CountryChina
- Language:Chinese
-
Abstract:
Bone marrow stromal cells(BMSCs) is a kind of adult stem cells which exists widely in human mesenchymal tissues and have active abilities of self-replication and multi-differentiation. When intervened individually or jointly by certain inducing agents and by the kind of genes, it can differentiate into specific lineage of cells in vitro and the capacity of multilineage differentiation and proliferation does not change. At the same time, with the unique immunological characteristics,it is an ideal seed cell for tissue engineering. In recent years, a lot of studies have proved that BMSCs can not only be induced and differentiate into nerve cells under certain conditions but have a certain structure and function of the nerve cells, which provide a new way in the treatment of nerve system diseases.This paper gives a review of studies on induced differentiation of BMSCs into nerve cells and the functions.
