Multidrug Resistance of Acinetobacter baumanii and Homogeneous Analysis
- VernacularTitle:多药耐药鲍氏不动杆菌基因同源性分析及流行病学调查
- Author:
Bin YAO
;
He WANG
;
Juan WANG
;
Baoxin ZHOU
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
Drug resistance;
Isolate;
Intensive care unit;
Homogeneous;
Prevalence
- From:
Chinese Journal of Nosocomiology
2009;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To understand the drug-resistant status of Acinetobacter baumanii and provide scientific basis for infection treatment.METHODS Eight multidrug-resistant A.baumannii(MDR-AB) strains isolated from nosocomial inpatients in intensive care unit(ICU) were collected in May 2007 and tested for drug sensitivity and MIC determination as well.We typed A.baumannii isolates with pulsed-field gel electrophoresis(PFGE) to determine whether they derived from the same clone.RESULTS Four isolates from nosocomial inpatients were resistant to multiple antibiotics including carbapenem.The PFGE types identified from eight isolates were same.All A.baumannii isolates are closely related.CONCLUSIONS The prevalence of nosocomial infection is due to transmission of the same strains among the patients in ICU.This finding highly suggests that isolate 1 was the source of this nosocomial infection and the problem of hand hygiene maybe the main transmission route.
