The effect of atorvastatin pretreatment on oxygen free radical after reperfusion in patients undergoning primary percutaneous coronary interventions
- VernacularTitle:阿托伐他汀对急诊经皮冠状动脉介入治疗患者再灌注后氧自由基的影响
- Author:
Miao CHEN
;
Hongwei LI
;
Yongliang WANG
- Publication Type:Journal Article
- Keywords:
Myocardiall reperfusion injury;
Reactive oxygen species;
Atorvastatin
- From:
Chinese Journal of Interventional Cardiology
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05) between the two groups.After the reperfusion,an absolute reduction of peak CK-MB can be observed in the atorvastatin group compared with the control group(253.24?35.21 U/L vs 361.30?26.31 U/L,P=0.040) whereas the SOD levels of the atorvastin group was higher than that in the control group(40.10?2.15 U/mL vs 36.05?6.97 U/mL,P=0.037).Conclusions Atorvastatin can reduce oxygen free radical produced during reperfusion,playing a protective role for the myocardial cell during I/R injury.
