Clinical and pathological features of Churge-Strauss syndrome combined leukocytoclastic vasculitis(report of 1 case)
- VernacularTitle:Churge-Strauss综合征合并白细胞碎裂性血管炎的临床及病理学特点(附1例报告)
- Author:
Donghong HUANG
;
Jinou ZHENG
;
Xiaoli CAO
- Publication Type:Journal Article
- Keywords:
Churge-Strauss syndrome;
leukocytoclastic vasculitis;
clinic;
pathology
- From:
Journal of Clinical Neurology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and pathological features of Churge-Strauss syndrome(CSS) combined leukocytoclastic vasculitis.Methods The clinical data of 1 patient with CSS combined leukocytoclastic vasculitis was analyzed retrospectively.Results The main symptoms of the case were peripheral nerve damage,violation of the skin lesions,gastrointestinal tract,lung,and central nervous system;peripheral blood eosinophil count was high.The pathological examine showed vessel wall and skin organizations had a large number of eosinophils infiltration,small vessel walls,as well as granuloma formation around multiple segmental fibrinoid necrotizing vasculitis.Eventually died of multiple organ failure.Conclusion The clinical manifestations of CSS combined leukocytoclastic vasculitis have vasculitis and peripheral neuropathy mainly;the pathological features are that vessel wall and skin organizations have a large number of inflammatory cells infiltration;the late multi-system are involved,and the prognosis is poor.
