Application and complication of cranial scaffold following craniocerebral injury:A contrast analysis
- VernacularTitle:颅脑支架在颅脑损伤中的应用及其并发症:优劣分析
- Author:
Jingjun HU
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(43):-
- CountryChina
- Language:Chinese
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Abstract:
OBJECTIVE:To investigate the current situation of cranial scaffold for the treatment of craniocerebral injury,analyze biocompatibility of the cranial scaffold,and observe the cranial scaffold-induced complications. METHODS:A computer-based online search was conducted in CNKI and Medline database in accordance with inclusion and exclusion criteria from 1988 to 2009. A total of 37 articles were included in the final analysis,which were summarized based on application situation of cranial scaffold for the treatment of craniocerebral injury,biocompatibility of cranial scaffold,and cranial scaffold-induced complication. RESULTS:Cranial scaffold had a good effect on the treatment of craniocerebral injury which was hard to be treated using surgical intervention and drug therapy. The biocompatibility of cranial scaffold might influence its security and efficiency. The poor biocompatibility of cranial scaffold increased incidence of varying complications,including thrombosis,cerebral hemorrhage,restenosis,hypertransfusion,and hypoperfusion. Therefore,patients should be cared carefully following scaffold implantation. CONCLUSION:Cranial scaffold implantation has a good effect on the treatment of craniocerebral injury; however,its biocompatibility to human body may cause complications which attract much attention by physicians.
