Relationships Between Antimicrobial Use and Producing Extended-spectrum ?-Lactamases
- VernacularTitle:抗菌药物使用与产超广谱?-内酰胺酶的关系
- Author:
Yawen GAO
;
Yu YANG
;
Yuetao WU
;
Wei CAO
;
Qiwei ZHOU
- Publication Type:Journal Article
- Keywords:
Antimicrobial;
Nosocomial infection;
Extended-spectrum ?-lactamases;
ECO;
KPN
- From:
Chinese Journal of Nosocomiology
2009;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the relationships between antimicrobial usage and the isolated rate of ESBLs-KPN and ESBLs-ECO.METHODS We monitored the data on the yearly patient-days and the yearly consumption(defined daily dose(DDD) per 1000 patient days) frequent antibiotics and the isolated rate of ESBLs-KPN and ESBLs-ECO causing nosocomial infections from Jan 2004 to Dec 2007 was analyzed.RESULTS The yearly patient-days of our department significantly increased from 64 203 days in 2004 to 74 442 days in 2007(P
