Pulmonary Fungal Infection and Resistance in Older Chronic Obstructive Pulmonary Disease Patients with Mechanical Ventilation
- VernacularTitle:老年慢性阻塞性肺疾病机械通气患者肺部真菌感染的分析
- Author:
Yong WANG
;
Lei PAN
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Pulmonary fungal infection
- From:
Chinese Journal of Nosocomiology
2009;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate pulmonary fungal infection spectrum and its resistance in older COPD patients with mechanical ventilation.METHODS Retrospective study were performed in 67 cases of COPD patients with mechanical ventilation treatment who were admitted to our ICU from Jan 2004 to Doc 2007.Bronchoalveolar lavage fluid was cultured,differentiation and antifungal susceptilibity testing were taken.RESULTS Seventy-eight fungi strains were cultured in 78 cases,among them,41 strains were Candida albicans(52.56%),14 of C.tropicalis,9 of C.krusei,5 of C.parapsilosis,7 of yeast-like fungi and 2 of Aspergillus.CONCLUSIONS There were increasing fungal infection rate in older COPD patients with mechanical ventilation and C.albicans is still the most frequent type.The resistance to triazole antifungal drug is also increasing.