Role of CD147 in tumorigenesis and metastasis:An update
- VernacularTitle:CD147在肿瘤发生及转移中的作用研究进展
- Author:
Bo WANG
;
Lirong ZHANG
;
Shukui WANG
- Publication Type:Journal Article
- Keywords:
CD147;
Tumor;
Tumorigenesis;
Metastasis
- From:
Journal of Medical Postgraduates
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
CD147 is a widely distributed cell surface glycoprotein that belongs to the Ig superfamily and is involved in various physiological and pathological activities.Highly expressed on the surface of many tumor cells,CD147 can promote tumor metastasis,angiogenesis and anchorage-independent growth.Targeting CD147 in cancer appears a promising therapeutic strategy.This review outlines the recent findings concerning the role of CD147 in tumor progression.
