Surveillance of High-level Gentamicin Resistance of Enterococcus and Analysis of Its Drug Resistance
- VernacularTitle:耐高浓度庆大霉素肠球菌检测及药敏结果分析
- Author:
Jun MENG
;
Junli ZHANG
;
Sufang GUO
- Publication Type:Journal Article
- Keywords:
Enterococcus;
Drug resistance;
High-level gentamicin
- From:
Chinese Journal of Nosocomiology
2009;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study resistance of Enterococcus in clinical isolates to high-level gentamicin(HLG) and investigate drug resistance of these Enterococcus.METHODS Totally 140 strains of Enterococcus were detected resistance to antibiotics by Kirby-Bauer test and agar-screening test.Data were analyzed using WHONET5.3 software.RESULTS Same result was obtained by two kinds of detecting methods,there were 73 strains of high level gentamicin resistance(HLGR,52.1%) and 67 strains of non-HLGR(47.9%),the resistance rate of HLGR was higher than that of non-HLGR,the isolation rate of vancomycin resistanct Enterococcus was 3.6%.CONCLUSIONS The most common enterococci causing hospital infection are E.faecalis and E.faecium.The drug resistance rate of E.faecium is higher than that of E.faecalis.It is imperative to select the proper method to detect HLGR of Enterococcus,and select proper antibiotic in terms of antibiotic susceptibility test during clinical therapy.
